MATK 抗体 (Internal Region)
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Quick Overview for MATK 抗体 (Internal Region) (ABIN7222372)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Lsk Polyclonal Antibody
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特异性
- Lsk Polyclonal Antibody detects endogenous levels of Lsk protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Lsk
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- Lsk
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背景
- Rabbit Anti-Lsk Polyclonal Antibody,MATK, CTK, HYL, Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK,The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: sRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,Megakaryocyte-associated tyrosine-protein kinase
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分子量
- observerd band 56kDa
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基因ID
- 4145
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UniProt
- P42679
抗原
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