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MED23 抗体 (AA 10-90)

This anti-MED23 antibody is a 兔 多克隆 antibody detecting MED23 in ELISA, WB, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7214346
发货至: 中国

Quick Overview for MED23 抗体 (AA 10-90) (ABIN7214346)

抗原

See all MED23 抗体
MED23 (Mediator Complex Subunit 23 (MED23))

适用

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人, 大鼠, 小鼠

宿主

  • 46
  • 1

克隆类型

  • 46
  • 1
多克隆

标记

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This MED23 antibody is un-conjugated

应用范围

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  • 19
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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 10-90

    原理

    CRSP130 Polyclonal Antibody

    特异性

    CRSP130 Polyclonal Antibody detects endogenous levels of CRSP130 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human CRSP130 at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MED23 (Mediator Complex Subunit 23 (MED23))

    别名

    CRSP130

    背景

    Rabbit Anti-CRSP130 Polyclonal Antibody,MED23, ARC130, CRSP3, DRIP130, KIAA1216, SUR2, Mediator of RNA polymerase II transcription subunit 23, Activator-recruited cofactor 130 kDa component, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP complex subu,The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. Mediator complex subunit 23 encoded by MED23 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for MED23.,Mediator of RNA polymerase II transcription subunit 23

    分子量

    observerd band 150kDa

    基因ID

    9439

    UniProt

    Q9ULK4

    途径

    Regulation of Lipid Metabolism by PPARalpha
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