MED13 抗体 (AA 650-730)
Quick Overview for MED13 抗体 (AA 650-730) (ABIN7226192)
抗原
See all MED13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 650-730
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原理
- TRAP240 Polyclonal Antibody
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特异性
- TRAP240 Polyclonal Antibody detects endogenous levels of TRAP240 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TRAP240 at AA range: 650-730
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MED13 (Mediator Complex Subunit 13 (MED13))
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别名
- TRAP240
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背景
- Rabbit Anti-TRAP240 Polyclonal Antibody,MED13, ARC250, KIAA0593, THRAP1, TRAP240, Mediator of RNA polymerase II transcription subunit 13, Activator-recruited cofactor 250 kDa component, ARC250, Mediator complex subunit 13, Thyroid hormone receptor-associated protein 1, Thyroid ho,MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of MED13 is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.,Mediator of RNA polymerase II transcription subunit 13
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基因ID
- 9969
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UniProt
- Q9UHV7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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