MED12 抗体 (AA 580-660)
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Quick Overview for MED12 抗体 (AA 580-660) (ABIN7226190)
抗原
See all MED12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 580-660
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原理
- TRAP230 Polyclonal Antibody
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特异性
- TRAP230 Polyclonal Antibody detects endogenous levels of TRAP230 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TRAP230 at AA range: 580-660
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亚型
- IgG
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anti-Mediator Complex Subunit 12 (MED12) (AA 1991-2025), (C-Term) antibody
MED12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52354 unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1742-2011) antibodyMED12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) antibodyMED12 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1829-1941) antibodyMED12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 251-350) antibodyMED12 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MED12 (Mediator Complex Subunit 12 (MED12))
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别名
- TRAP230
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背景
- Rabbit Anti-TRAP230 Polyclonal Antibody,MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230, Mediator of RNA polymerase II transcription subunit 12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45, Mediator complex subunit 12, OPA-containing prote,The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1. MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by the gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome.,Mediator of RNA polymerase II transcription subunit 12
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基因ID
- 9968
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UniProt
- Q93074
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
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