MDC1 抗体 (pSer513)
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北京 101111
Quick Overview for MDC1 抗体 (pSer513) (ABIN7226058)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer513
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原理
- Rabbit Anti-MDC1 (phospho Ser513) Polyclonal Antibody
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特异性
- Phospho-MDC1 (S513) Polyclonal Antibody detects endogenous levels of MDC1 protein only when phosphorylated at S513.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human MDC1 Phospho-Ser513
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亚型
- IgG
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anti-Mdc1 (MDC1) antibody
MDC1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 31-130) antibodyMDC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 APC
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 390)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 Atto 390
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 488)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 Atto 488
anti-Mdc1 (MDC1) (N-Term) antibody (PerCP)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 PerCP
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 594)MDC1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal P2B11 Atto 594
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MDC1 (Mdc1 (MDC1))
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别名
- MDC1
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背景
- MDC1, KIAA0170, NFBD1, Mediator of DNA damage checkpoint protein 1, Nuclear factor with BRCT domains 1The protein encoded by MDC1 (mediator of DNA damage checkpoint 1) contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
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基因ID
- 9656
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UniProt
- Q14676
抗原
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