MCF2L 抗体
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北京 101111
Quick Overview for MCF2L 抗体 (ABIN7229596)
抗原
See all MCF2L 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-MCF2L Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MCF2L protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human MCF2L protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MCF2L (MCF.2 Cell Line Derived Transforming Sequence-Like (MCF2L))
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别名
- MCF2L
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背景
- Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like proteinMCF2L encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. MCF2L (MCF. Cell Line Derived Transforming Sequence Like) is a Protein Coding gene. Diseases associated with MCF2L include Atypical Autism and Osteoarthritis. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway.
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分子量
- 125kD
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基因ID
- 23263
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UniProt
- O15068
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途径
- Neurotrophin Signaling Pathway, Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis
抗原
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