MXD4 抗体 (AA 10-90)
Quick Overview for MXD4 抗体 (AA 10-90) (ABIN7219076)
抗原
See all MXD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Mad 4 Polyclonal Antibody
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特异性
- Mad 4 Polyclonal Antibody detects endogenous levels of Mad 4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Mad 4 at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MXD4 (MAX Dimerization Protein 4 (MXD4))
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别名
- Mad 4
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背景
- Rabbit Anti-Mad 4 Polyclonal Antibody,MXD4, BHLHC12, MAD4, Max dimerization protein 4, Max dimerizer 4, Class C basic helix-loop-helix protein 12, bHLHc12, Max-associated protein 4, Max-interacting transcriptional repressor MAD4,MXD4 is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.,Max dimerization protein 4
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基因ID
- 10608
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UniProt
- Q14582
抗原
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