MMP17 抗体 (Cleaved-Gln129)
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北京 101111
Quick Overview for MMP17 抗体 (Cleaved-Gln129) (ABIN7212492)
抗原
See all MMP17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160, Cleaved-Gln129
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原理
- Cleaved-MMP-17 (Q129) Polyclonal Antibody
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特异性
- Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MMP-17 at AA range: 80-160
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亚型
- IgG
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anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibody
MMP17 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (AA 432-460), (C-Term) antibodyMMP17 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33781 unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (cleaved), (Internal Region) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibodyMMP17 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (cleaved), (Gln129) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (AA 391-420) antibodyMMP17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2033-2034 unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (Middle Region) antibodyMMP17 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
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别名
- MMP-17
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背景
- Rabbit Anti-Cleaved-MMP-17 (Q129) Polyclonal Antibody,MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP,MMP17 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 17 is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of matrix metallopeptidase 17 protein has been observed in osteoarthritis and multiple human cancers.,Matrix metalloproteinase-17
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分子量
- observerd band 53kDa
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基因ID
- 4326
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UniProt
- Q9ULZ9
抗原
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