MMP1 抗体 (AA 190-270)
Quick Overview for MMP1 抗体 (AA 190-270) (ABIN7212532)
抗原
See all MMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-270
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原理
- MMP-1 Polyclonal Antibody
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特异性
- MMP-1 Polyclonal Antibody detects endogenous levels of MMP-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MMP-1 at AA range: 190-270
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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别名
- MMP-1
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背景
- Rabbit Anti-MMP-1 Polyclonal Antibody,MMP1, CLG, Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1,MMP1 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease (matrix metallopeptidase 1) breaks down the interstitial collagens, including types I, II, and III. MMP1 is part of a cluster of MMP genes on chromosome 11. Mutations in MMP1 are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Interstitial collagenase
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分子量
- observerd band 55kDa
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基因ID
- 4312
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UniProt
- P03956
抗原
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