MRGPRX1 抗体 (AA 240-320)
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北京 101111
Quick Overview for MRGPRX1 抗体 (AA 240-320) (ABIN7220926)
抗原
See all MRGPRX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-320
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原理
- MRGX1 Polyclonal Antibody
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特异性
- MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human MRGX1 at AA range: 240-320
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亚型
- IgG
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anti-MAS-Related GPR, Member X1 (MRGPRX1) antibody
MRGPRX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (N-Term) antibodyMRGPRX1 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (AA 263-322) antibodyMRGPRX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (C-Term) antibodyMRGPRX1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) antibodyMRGPRX1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member X1 (MRGPRX1) (AA 271-320) antibodyMRGPRX1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
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别名
- MRGX1
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背景
- Rabbit Anti-MRGX1 Polyclonal Antibody,MRGPRX1, MRGX1, SNSR3, SNSR4, Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4,MRGPRX1 (MAS Related GPR Family Member X1) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. rphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed: 26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.,Mas-related G-protein coupled receptor member X1
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分子量
- observerd band 36kDa
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基因ID
- 259249
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UniProt
- Q96LB2
抗原
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