MADD 抗体 (AA 720-800)
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北京 101111
Quick Overview for MADD 抗体 (AA 720-800) (ABIN7215662)
抗原
See all MADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-800
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原理
- Rabbit Anti-MADD Polyclonal Antibody
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特异性
- MADD Polyclonal Antibody detects endogenous levels of MADD protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human MADD at AA range: 720-800
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亚型
- IgG
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anti-MAP-Kinase Activating Death Domain (MADD) antibody
KD Validated MADD 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB110 unconjugated Recombinant Antibody
anti-MAP-Kinase Activating Death Domain (MADD) antibodyMADD 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (C-Term) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 1597-1647) antibodyMADD 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibodyMADD 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 751-800) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 1597-1647) antibodyMADD 适用: 人 WB, IF (p), IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (C-Term) antibodyMADD 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MADD (MAP-Kinase Activating Death Domain (MADD))
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别名
- MADD
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背景
- MADD, DENN, IG20, KIAA0358, MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells, Insulinoma glucagonoma clone 20, Rab3 GDP/GTP exchange factorTumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. MAP kinase-activating death domain protein encoded by MADD is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
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分子量
- 183kD
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基因ID
- 8567
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UniProt
- Q8WXG6
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途径
- Caspase Cascade in Apoptosis
抗原
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