MDH1 抗体
Our Local Distributor
北京 101111
Quick Overview for MDH1 抗体 (ABIN7229614)
抗原
See all MDH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MDHC Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of MDHC protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human MDHC protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))
-
别名
- MDHC
-
背景
- Rabbit Anti-MDHC Polyclonal Antibody,Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase,MDH1 encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.,MDHC
-
分子量
- observerd band 36kDa
-
基因ID
- 4190
-
UniProt
- P40925
抗原
-