MPHOSPH8 抗体 (AA 290-370)
This 兔 多克隆 antibody specifically detects MPHOSPH8 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7229744
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for MPHOSPH8 抗体 (AA 290-370) (ABIN7229744)
抗原
See all MPHOSPH8 抗体
MPHOSPH8
(M-Phase phosphoprotein 8 (MPHOSPH8))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This MPHOSPH8 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 290-370
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原理
- Rabbit Anti-MPP8 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MPP8 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human MPP8 protein at AA range: 290-370
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亚型
- IgG
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anti-M-Phase phosphoprotein 8 (MPHOSPH8) (AA 1-259) antibody
MPHOSPH8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MPHOSPH8 (M-Phase phosphoprotein 8 (MPHOSPH8))
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别名
- MPP8
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背景
- M-phase phosphoprotein 8, Two hybrid-associated protein 3 with RanBPM, Twa3MPHOSPH8 (M-Phase Phosphoprotein 8) is a Protein Coding gene. Heterochromatin component that specifically recognizes and binds methylated Lys-9 of histone H3 and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites, these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.
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分子量
- 94kD
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基因ID
- 54737
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UniProt
- Q99549
抗原
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