KDM5B 抗体
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北京 101111
Quick Overview for KDM5B 抗体 (ABIN7229274)
抗原
See all KDM5B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-KDM5B Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of KDM5B protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human KDM5B protein
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibody
KDM5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H3D7 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 65-165) antibodyKDM5B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 1494-1544) antibodyKDM5B 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 784-883) antibodyKDM5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 1494-1544) antibodyKDM5B 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 641-685), (Middle Region) antibodyKDM5B 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) antibodyKDM5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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别名
- KDM5B
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背景
- Lysine-specific demethylase 5B, Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1KDM5B encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. KDM5B (Lysine Demethylase 5B) is a Protein Coding gene. Diseases associated with KDM5B include Ascending Colon Cancer and Autosomal Dominant Non-Syndromic Intellectual Disability. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.
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分子量
- 169kD
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基因ID
- 10765
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UniProt
- Q9UGL1
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途径
- Warburg Effect
抗原
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