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KDM5B 抗体

This anti-KDM5B antibody is a 兔 多克隆 antibody detecting KDM5B in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7229274
发货至: 中国

Quick Overview for KDM5B 抗体 (ABIN7229274)

抗原

See all KDM5B 抗体
KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

适用

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  • 1
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人, 小鼠

宿主

  • 41
  • 7

克隆类型

  • 42
  • 6
多克隆

标记

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  • 1
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This KDM5B antibody is un-conjugated

应用范围

  • 37
  • 17
  • 16
  • 13
  • 13
  • 5
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  • 3
  • 2
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Western Blotting (WB), ELISA
  • 原理

    KDM5B Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of KDM5B protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human KDM5B protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

    别名

    KDM5B

    背景

    Rabbit Anti-KDM5B Polyclonal Antibody,Lysine-specific demethylase 5B, Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1,KDM5B encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. KDM5B (Lysine Demethylase 5B) is a Protein Coding gene. Diseases associated with KDM5B include Ascending Colon Cancer and Autosomal Dominant Non-Syndromic Intellectual Disability. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.,KDM5B

    分子量

    observerd band 169kDa

    基因ID

    10765

    UniProt

    Q9UGL1

    途径

    Warburg Effect
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