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LAT 抗体

This 兔 多克隆 anti-LAT antibody specifically detects LAT in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7215588
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LAT 抗体 (ABIN7215588)

抗原

See all LAT 抗体
LAT (Linker For Activation of T Cells (LAT))

适用

  • 134
  • 55
  • 39
  • 1
人, 小鼠, 大鼠

宿主

  • 127
  • 10
  • 2
  • 1

克隆类型

  • 109
  • 31
多克隆

标记

  • 71
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This LAT antibody is un-conjugated

应用范围

  • 98
  • 45
  • 39
  • 39
  • 35
  • 18
  • 15
  • 12
  • 9
  • 8
  • 5
  • 1
  • 1
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Western Blotting (WB), ELISA
  • 原理

    LAT Polyclonal Antibody

    特异性

    LAT Polyclonal Antibody detects endogenous levels of LAT protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human LAT around the non-phosphorylation site of Y200

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    LAT (Linker For Activation of T Cells (LAT))

    别名

    LAT

    背景

    Rabbit Anti-LAT Polyclonal Antibody,LAT, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38,Linker for activation of T-cells family member 1 encoded by LAT is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.,Linker for activation of T-cells family member 1

    分子量

    observerd band 38kDa

    基因ID

    27040

    UniProt

    O43561

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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