LIMK2 抗体 (pThr505)
Quick Overview for LIMK2 抗体 (pThr505) (ABIN7213030)
抗原
See all LIMK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr505
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原理
- LIMK-2 (phospho Thr505) Polyclonal Antibody
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特异性
- Phospho-LIMK-2 (T505) Polyclonal Antibody detects endogenous levels of LIMK-2 protein only when phosphorylated at T505.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human LIMK-2 Phospho-Thr505
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亚型
- IgG
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anti-LIM Domain Kinase 2 (LIMK2) (pSer283) antibody
LIMK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H2-E11 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (pThr505) antibodyLIMK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) antibodyLIMK2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (Ser283) antibodyLIMK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 181-193) antibodyVerified LIMK2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 461-510) antibodyLIMK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- LIMK2 (LIM Domain Kinase 2 (LIMK2))
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别名
- LIMK-2
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背景
- Rabbit Anti-LIMK-2 (phospho Thr505) Polyclonal Antibody,LIMK2, LIM domain kinase 2, LIMK-2,There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIM domain kinase 2 encoded by LIMK2 is phosphorylated and activated by ROCK, a downstream effector of Rho, and LIM domain kinase 2, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for LIMK2.,LIM domain kinase 2
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基因ID
- 3985
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UniProt
- P53671
抗原
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