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LIM Domain Binding 3 Protein 抗体 (AA 41-90)

This 兔 多克隆 anti-LIM Domain Binding 3 Protein antibody specifically detects LIM Domain Binding 3 Protein in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7229370
发货至: 中国
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Quick Overview for LIM Domain Binding 3 Protein 抗体 (AA 41-90) (ABIN7229370)

抗原

See all LIM Domain Binding 3 Protein (LDB3) 抗体
LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

适用

  • 22
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 19
  • 4
  • 1

克隆类型

  • 21
  • 3
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
This LIM Domain Binding 3 Protein antibody is un-conjugated

应用范围

  • 23
  • 14
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-90

    原理

    LDB3 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of LDB3 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human LDB3 protein at AA range: 41-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

    别名

    LDB3

    背景

    Rabbit Anti-LDB3 Polyclonal Antibody,LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein,LDB3 encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by LDB3 interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in LDB3 have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.,LDB3

    分子量

    observerd band 79kDa

    基因ID

    11155

    UniProt

    O75112
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