LINGO1 抗体 (AA 370-450)
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北京 101111
Quick Overview for LINGO1 抗体 (AA 370-450) (ABIN7229400)
抗原
See all LINGO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-450
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原理
- Rabbit Anti-LIGO1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of LIGO1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human LIGO1 protein at AA range: 370-450
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亚型
- IgG
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anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 575-603), (C-Term) antibody
LINGO1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15362 unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 521-620) antibodyLINGO1 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 42-240) antibodyLINGO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 62-92), (N-Term) antibodyLINGO1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8949 unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (C-Term) antibodyLINGO1 适用: 人, 小鼠, 大鼠, Cow, 猴, Pig, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 507-521), (Extracellular), (N-Term) antibodyLINGO1 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (Internal Region) antibodyLINGO1 适用: 人, 小鼠, 大鼠, Cow, 猴, Pig, 犬, 马, 兔, 斑马鱼 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 364-620) antibodyLINGO1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (AA 57-85), (N-Term) antibodyLINGO1 适用: 人 WB 宿主: 兔 Polyclonal RB22992 unconjugated
anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (pSer596) antibodyLINGO1 适用: 人 DB 宿主: 兔 Polyclonal RB15362 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
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别名
- LIGO1
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背景
- Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6ALINGO1 (Leucine Rich Repeat And Ig Domain Containing 1) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. GO annotations related to this gene include epidermal growth factor receptor binding. An important paralog of this gene is LINGO2. Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed: 14966521, PubMed: 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed: 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
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分子量
- 68kD
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基因ID
- 84894
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UniProt
- Q96FE5
抗原
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