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LINGO1 抗体 (AA 370-450)

This 兔 多克隆 anti-LINGO1 antibody specifically detects LINGO1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7229400
发货至: 中国
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Quick Overview for LINGO1 抗体 (AA 370-450) (ABIN7229400)

抗原

See all LINGO1 抗体
LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This LINGO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 370-450

    原理

    LIGO1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of LIGO1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human LIGO1 protein at AA range: 370-450

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

    别名

    LIGO1

    背景

    Rabbit Anti-LIGO1 Polyclonal Antibody,Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A,LINGO1 (Leucine Rich Repeat And Ig Domain Containing 1) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. GO annotations related to this gene include epidermal growth factor receptor binding. An important paralog of this gene is LINGO2. Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed: 14966521, PubMed: 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed: 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).,LIGO1

    分子量

    observerd band 68kDa

    基因ID

    84894

    UniProt

    Q96FE5
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