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Leptin Receptor 抗体 (Internal Region)

This 兔 多克隆 anti-Leptin Receptor antibody specifically detects Leptin Receptor in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7218100
发货至: 中国
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Quick Overview for Leptin Receptor 抗体 (Internal Region) (ABIN7218100)

抗原

See all Leptin Receptor (LEPR) 抗体
Leptin Receptor (LEPR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Leptin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    Internal Region

    原理

    Ob-R Polyclonal Antibody

    特异性

    Ob-R Polyclonal Antibody detects endogenous levels of Ob-R protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Ob-R

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Leptin Receptor (LEPR)

    别名

    Ob-R

    背景

    Rabbit Anti-Ob-R Polyclonal Antibody,LEPR, DB, OBR, Leptin receptor, LEP-R, HuB219, OB receptor, OB-R, CD295,Leptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID: 54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID: 9207021).,Leptin receptor

    分子量

    observerd band 132kDa

    基因ID

    3953

    UniProt

    P48357

    途径

    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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