Leptin Receptor 抗体 (pTyr1141)
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Quick Overview for Leptin Receptor 抗体 (pTyr1141) (ABIN7213352)
抗原
See all Leptin Receptor (LEPR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1141
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原理
- Ob-R (phospho Tyr1141) Polyclonal Antibody
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特异性
- Phospho-Ob-R (Y1141) Polyclonal Antibody detects endogenous levels of Ob-R protein only when phosphorylated at Y1141.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Ob-R Phospho-Tyr1141
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亚型
- IgG
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anti-Leptin Receptor (LEPR) (AA 901-1000) antibody
LEPR 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 310-539) antibodyLEPR 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 22-203) antibodyLEPR 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 238-375) antibodyLEPR 适用: 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (Internal Region) antibodyVerified LEPR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 777-791), (Extracellular) antibodyLEPR 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) antibodyLEPR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 23-52) antibodyLEPR 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 501-600) antibodyLEPR 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) antibodyLEPR 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15785 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Leptin Receptor (LEPR)
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别名
- Ob-R
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背景
- Rabbit Anti-Ob-R (phospho Tyr1141) Polyclonal Antibody,LEPR, DB, OBR, Leptin receptor, LEP-R, HuB219, OB receptor, OB-R, CD antigen CD295,Leptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. Leptin receptor is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in LEPR have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for LEPR. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).,Leptin receptor
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分子量
- observerd band 132kDa
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基因ID
- 3953
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UniProt
- P48357
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途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
抗原
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