LMTK3 抗体 (AA 1220-1300)
Our Local Distributor
北京 101111
Quick Overview for LMTK3 抗体 (AA 1220-1300) (ABIN7219336)
抗原
See all LMTK3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1220-1300
-
原理
- LMTK3 Polyclonal Antibody
-
特异性
- LMTK3 Polyclonal Antibody detects endogenous levels of LMTK3 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human LMTK3 at AA range: 1220-1300
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))
-
别名
- LMTK3
-
背景
- Rabbit Anti-LMTK3 Polyclonal Antibody,LMTK3, KIAA1883, TYKLM3, Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3,LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).,serine threonine-protein kinase LMTK3
-
分子量
- observerd band 40kDa
-
基因ID
- 114783
-
UniProt
- Q96Q04
抗原
-