LGMN 抗体 (AA 60-140)
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Quick Overview for LGMN 抗体 (AA 60-140) (ABIN7229390)
抗原
See all LGMN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-140
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原理
- LGMN Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of LGMN protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human LGMN protein at AA range: 60-140
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亚型
- IgG
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anti-Legumain (LGMN) (AA 18-433) antibody
LGMN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-435) antibodyLGMN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 201-300) antibodyLGMN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-323) antibodyLGMN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) antibodyLGMN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) antibodyKD Validated LGMN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2095 unconjugated Recombinant Antibody
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 199-312) antibodyLGMN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- LGMN (Legumain (LGMN))
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别名
- LGMN
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背景
- Rabbit Anti-LGMN Polyclonal Antibody,Legumain, Asparaginyl endopeptidase, Protease, cysteine 1,LGMN encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of LGMN may be associated with the majority of solid tumor types. LGMN has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.,LGMN
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分子量
- observerd band 47kDa
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基因ID
- 5641
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UniProt
- Q99538
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途径
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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