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Latrophilin 1 抗体 (AA 530-610)

This anti-Latrophilin 1 antibody is a 兔 多克隆 antibody detecting Latrophilin 1 in ELISA 和 IF. Suitable for 大鼠, 人 和 小鼠.
产品编号 ABIN7220562
发货至: 中国

Quick Overview for Latrophilin 1 抗体 (AA 530-610) (ABIN7220562)

抗原

See all Latrophilin 1 (LPHN1) 抗体
Latrophilin 1 (LPHN1)

适用

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  • 1
大鼠, 人, 小鼠

宿主

  • 34
  • 2

克隆类型

  • 34
  • 2
多克隆

标记

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This Latrophilin 1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 530-610

    原理

    Latrophilin-1 Polyclonal Antibody

    特异性

    Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Latrophilin-1 at AA range: 530-610

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Latrophilin 1 (LPHN1)

    别名

    Latrophilin-1

    背景

    Rabbit Anti-Latrophilin-1 Polyclonal Antibody,LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2,ADGRL1 encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.,Latrophilin-1

    基因ID

    22859

    UniProt

    O94910

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis
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