Latrophilin 1 抗体 (AA 530-610)
Quick Overview for Latrophilin 1 抗体 (AA 530-610) (ABIN7220562)
抗原
See all Latrophilin 1 (LPHN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 530-610
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原理
- Latrophilin-1 Polyclonal Antibody
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特异性
- Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Latrophilin-1 at AA range: 530-610
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Latrophilin 1 (LPHN1)
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别名
- Latrophilin-1
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背景
- Rabbit Anti-Latrophilin-1 Polyclonal Antibody,LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2,ADGRL1 encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.,Latrophilin-1
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基因ID
- 22859
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UniProt
- O94910
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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