KSR1 抗体 (pSer392)
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北京 101111
Quick Overview for KSR1 抗体 (pSer392) (ABIN7213238)
抗原
See all KSR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer392
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原理
- Rabbit Anti-Ksr-1 (phospho Ser392) Polyclonal Antibody
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特异性
- Phospho-Ksr-1 (S392) Polyclonal Antibody detects endogenous levels of Ksr-1 protein only when phosphorylated at S392.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Ksr-1 Phospho-Ser392
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亚型
- IgG
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anti-Kinase Suppressor of Ras 1 (KSR1) antibody
KD Validated KSR1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB6290 unconjugated Recombinant Antibody
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 301-400) antibodyKSR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 404-598) antibodyKSR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 320-420) antibodyKSR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 358-407) antibodyKSR1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 601-750) antibodyKSR1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (Tyr40) antibodyKSR1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) antibodyKSR1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 301-400) antibodyKSR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) antibodyKSR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- KSR1 (Kinase Suppressor of Ras 1 (KSR1))
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别名
- Ksr-1
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背景
- KSR1, KSR, Kinase suppressor of Ras 1Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFβ-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFβ stimulation.
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分子量
- 115kD
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基因ID
- 8844
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UniProt
- Q8IVT5
抗原
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