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pan Keratin 抗体 (AA 150-220)

This 兔 多克隆 antibody specifically detects pan Keratin in IHC, WB 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7229282
发货至: 中国
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Room 801-803
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Quick Overview for pan Keratin 抗体 (AA 150-220) (ABIN7229282)

抗原

See all pan Keratin (panKRT) 抗体
pan Keratin (panKRT)

适用

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人, 大鼠, 小鼠

宿主

  • 108
  • 79
  • 3

克隆类型

  • 153
  • 37
多克隆

标记

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This pan Keratin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

    • 52
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    • 1
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    AA 150-220

    原理

    Rabbit Anti-Keratin-pan Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Keratin-pan

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human Keratin-pan protein at AA range: 150-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    pan Keratin (panKRT)

    别名

    Keratin-pan

    背景

    Keratin, type II cytoskeletal 2 epidermal, KRT2, Cytokeratin-2e, CK-2e, Epithelial keratin-2e, Keratin-2 epidermis, Keratin-2e, K2e, Type-II keratin Kb2, KRT2, KRT2A, KRT2EThe protein encoded by KRT2 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in KRT2 have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. KRT2 (Keratin 2) is a Protein Coding gene. Diseases associated with KRT2 include Ichthyosis Bullosa Of Siemens and Exfoliative Ichthyosis. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization.

    分子量

    70kD

    基因ID

    3849

    UniProt

    P35908, Q01546, P12035, P13647, P02538, P04259, P48668, Q3SY84, Q14CN4, Q86Y46, Q7RTS7, O95678, Q5XKE5, P08729, P05787, Q9NSB2
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