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KRT8 抗体

This anti-KRT8 antibody is a 兔 多克隆 antibody detecting KRT8 in WB, IF, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 猴.
产品编号 ABIN7214498
发货至: 中国

Quick Overview for KRT8 抗体 (ABIN7214498)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

适用

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人, 小鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    Cytokeratin 8 Polyclonal Antibody

    特异性

    Cytokeratin 8 Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Cytokeratin 8 around the non-phosphorylation site of S73

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    Cytokeratin 8

    背景

    Rabbit Anti-Cytokeratin 8 Polyclonal Antibody,KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8,KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.,Keratin type II cytoskeletal 8

    分子量

    observerd band 52kDa

    基因ID

    3856

    UniProt

    P05787
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