KRT4 抗体 (AA 200-260)
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北京 101111
Quick Overview for KRT4 抗体 (AA 200-260) (ABIN7228142)
抗原
See all KRT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-260
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原理
- Cytokeratin 4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of Cytokeratin 4
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human Cytokeratin 4 protein at AA range: 200-260
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- KRT4 (Keratin 4 (KRT4))
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别名
- Cytokeratin 4
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背景
- Rabbit Anti-Cytokeratin 4 Polyclonal Antibody,Keratin, type II cytoskeletal 4, Cytokeratin-4, CK-4, Keratin-4, K4, Type-II keratin Kb4,The protein encoded by KRT4 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. KRT4 (Keratin 4) is a Protein Coding gene. Diseases associated with KRT4 include White Sponge Nevus 1 and White Sponge Nevus Of Cannon, Krt4-Related. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization.,Cytokeratin 4
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分子量
- observerd band 57kDa
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UniProt
- P19013
抗原
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