Cytokeratin 13 抗体 (Internal Region)
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北京 101111
Quick Overview for Cytokeratin 13 抗体 (Internal Region) (ABIN7214478)
抗原
See all Cytokeratin 13 (KRT13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Rabbit Anti-Cytokeratin 13 Polyclonal Antibody
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特异性
- Cytokeratin 13 Polyclonal Antibody detects endogenous levels of Cytokeratin 13 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Cytokeratin 13
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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别名
- Cytokeratin 13
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背景
- KRT13, Keratin, type I cytoskeletal 13, Cytokeratin-13, CK-13, Keratin-13, K13Keratin 13 encoded by KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of KRT13 results in multiple transcript variants, however, not all variants have been described.
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分子量
- 52kD
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基因ID
- 3860
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UniProt
- P13646
抗原
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