JunB 抗体 (pSer79)
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北京 101111
Quick Overview for JunB 抗体 (pSer79) (ABIN7221958)
抗原
See all JunB (JUNB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer79
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原理
- Jun B (phospho Ser79) Polyclonal Antibody
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特异性
- Phospho-Jun B (S79) Polyclonal Antibody detects endogenous levels of Jun B protein only when phosphorylated at S79.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Jun B Phospho-Ser79
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IP (2-5 μg/mg lysate), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
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别名
- Jun B
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背景
- Rabbit Anti-Jun B (phospho Ser79) Polyclonal Antibody,JUNB, Transcription factor jun-B,JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML).,Transcription factor jun-B
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基因ID
- 3726
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UniProt
- P17275
抗原
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