IL5RA 抗体 (N-Term)
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Quick Overview for IL5RA 抗体 (N-Term) (ABIN7217964)
抗原
See all IL5RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- IL-5Rα Polyclonal Antibody
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特异性
- IL-5Rα Polyclonal Antibody detects endogenous levels of IL-5Rα protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human IL-5Ralpha
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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别名
- IL-5Ralpha
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背景
- Rabbit Anti-IL-5Rα Polyclonal Antibody,IL5RA, IL5R, Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CDw125, CD125,Interleukin-5 receptor subunit alpha encoded by IL5RA is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.,Interleukin-5 receptor subunit alpha
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分子量
- observerd band 47kDa
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基因ID
- 3568
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UniProt
- Q01344
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途径
- JAK/STAT Signaling
抗原
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