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IL12B 抗体 (Internal Region)

The 兔 多克隆 anti-IL12B antibody (ABIN7221802) specifically detects IL12B in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7221802
发货至: 中国
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Quick Overview for IL12B 抗体 (Internal Region) (ABIN7221802)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    Internal Region

    原理

    IL-12B Polyclonal Antibody

    特异性

    IL-12B Polyclonal Antibody detects endogenous levels of IL-12B protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human IL-12B

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL-12B

    背景

    Rabbit Anti-IL-12B Polyclonal Antibody,IL12B, NKSF2, Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, NKSF2,IL12B encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL12B has been reported to be associated with the severity of atopic and non-atopic asthma in children.,Interleukin-12 subunit beta

    分子量

    observerd band 40kDa

    基因ID

    3593

    UniProt

    P29460

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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