IFIT3 抗体 (AA 330-410)
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Quick Overview for IFIT3 抗体 (AA 330-410) (ABIN7229034)
抗原
See all IFIT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-410
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原理
- IFIT3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of IFIT3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human IFIT3 protein at AA range: 330-410
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))
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别名
- IFIT3
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背景
- Rabbit Anti-IFIT3 Polyclonal Antibody,Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60 kDa protein, IFI-60K, Interferon-induced protein with tetratricopeptide repeats 4, IFIT-4, Retinoic acid-induced gene G protein, P60, RIG-G,IFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3) is a Protein Coding gene. Among its related pathways are Interferon gamma signaling and Cytokine Signaling in Immune system. IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27.,IFIT3
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分子量
- observerd band 53kDa
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基因ID
- 3437
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UniProt
- O14879
抗原
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