IFIH1 抗体 (AA 940-1020)
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Quick Overview for IFIH1 抗体 (AA 940-1020) (ABIN7215708)
抗原
See all IFIH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 940-1020
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原理
- MDA5 Polyclonal Antibody
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特异性
- MDA5 Polyclonal Antibody detects endogenous levels of MDA5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human MDA5 at AA range: 940-1020
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亚型
- IgG
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anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-205) antibody
IFIH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (N-Term) antibodyVerified IFIH1 适用: 人, 猴 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 700-1025) antibodyIFIH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 612-661) antibodyIFIH1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyKD Validated IFIH1 适用: 人 WB 宿主: 兔 Monoclonal 24GB6085 unconjugated Recombinant Antibody
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-221) antibodyIFIH1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 928-1023) antibodyIFIH1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F6 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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别名
- MDA5
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背景
- Rabbit Anti-MDA5 Polyclonal Antibody,IFIH1, MDA5, RH116, Interferon-induced helicase C domain-containing protein 1, Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domai,DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 encodes a DEAD box protein, interferon-induced helicase C domain-containing protein 1, that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.,Interferon-induced helicase C domain-containing protein 1
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分子量
- observerd band 120kDa
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基因ID
- 64135
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UniProt
- Q9BYX4
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途径
- Activation of Innate immune Response
抗原
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