IFITM2 抗体 (Internal Region)
Quick Overview for IFITM2 抗体 (Internal Region) (ABIN7218574)
抗原
See all IFITM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- IFITM2 Polyclonal Antibody
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特异性
- IFITM2 Polyclonal Antibody detects endogenous levels of IFITM2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human IFITM2
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))
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别名
- IFITM2
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背景
- Rabbit Anti-IFITM2 Polyclonal Antibody,IFITM2, Interferon-induced transmembrane protein 2, Dispanin subfamily A member 2c, DSPA2c, Interferon-inducible protein 1-8D,IFITM2 (Interferon Induced Transmembrane Protein 2) is a Protein Coding gene. Diseases associated with IFITM2 include west nile virus and stomatitis. Among its related pathways are Immune System and Interferon gamma signaling. An important paralog of this gene is IFITM1. IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.,Interferon-induced transmembrane protein 2
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分子量
- observerd band 15kDa
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基因ID
- 10581
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UniProt
- Q01629
抗原
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