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ITGB3BP 抗体 (AA 10-90)

This 兔 多克隆 anti-ITGB3BP antibody specifically detects ITGB3BP in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7227848
发货至: 中国
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Quick Overview for ITGB3BP 抗体 (AA 10-90) (ABIN7227848)

抗原

See all ITGB3BP 抗体
ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

适用

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宿主

  • 21
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克隆类型

  • 21
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多克隆

标记

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This ITGB3BP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 2
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    AA 10-90

    原理

    CENPR Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CENPR protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CENPR protein at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

    别名

    CENPR

    背景

    Rabbit Anti-CENPR Polyclonal Antibody,Centromere protein R, CENP-R, Beta-3-endonexin, Integrin beta-3-binding protein, Nuclear receptor-interacting factor 3,ITGB3BP (Integrin Subunit Beta 3 Binding Protein) encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. ITGB3BP also acts as a corepressor of NF-kappaB-dependent signaling. ITGB3BP induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. ITGB3BP is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.,CENPR

    分子量

    observerd band 19kDa

    基因ID

    23421

    UniProt

    Q13352

    途径

    Neurotrophin Signaling Pathway
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