Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) 抗体
The 兔 多克隆 anti-Integrin AlphaV HC antibody (ABIN7212526) specifically detects Integrin AlphaV HC in ELISA 和 WB.
The antibody is reactive with 人 samples.
产品编号 ABIN7212526
发货至:
中国
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Quick Overview for Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) 抗体 (ABIN7212526)
抗原
Integrin AlphaV HC
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 810-890, Cleaved-Lys889
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原理
- Cleaved-Integrin αV HC (K889) Polyclonal Antibody
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特异性
- Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Integrin alphaV HC at AA range: 810-890
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亚型
- IgG
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anti-Integrin AlphaV HC (Lys889) antibody
适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Integrin AlphaV HC
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背景
- Rabbit Anti-Cleaved-Integrin αV HC (K889) Polyclonal Antibody,ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51,The product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.,Integrin alpha-V
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分子量
- observerd band 95kDa
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基因ID
- 3685
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UniProt
- P06756
抗原
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