ITGA7 抗体 (Cleaved-Glu959)
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北京 101111
Quick Overview for ITGA7 抗体 (Cleaved-Glu959) (ABIN7212524)
抗原
See all ITGA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 910-990, Cleaved-Glu959
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原理
- Rabbit Anti-Cleaved-Integrin α7 LC (E959) Polyclonal Antibody
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特异性
- Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human Integrin alpha7 LC at AA range: 910-990
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- ITGA7 (Integrin, alpha 7 (ITGA7))
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别名
- Integrin alpha7 LC
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背景
- ITGA7, Integrin alpha-7The protein encoded by ITGA7 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.Integrin subunit alpha 7 functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in ITGA7 are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for ITGA7.
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分子量
- 25kD
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基因ID
- 3679
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UniProt
- Q13683
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途径
- Integrin Complex
抗原
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