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ITGA7 抗体 (Cleaved-Glu959)

The 兔 多克隆 anti-ITGA7 antibody is suitable to detect ITGA7 in samples from 人 和 猴. It has been validated for WB 和 ELISA.
产品编号 ABIN7212524
发货至: 中国
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Quick Overview for ITGA7 抗体 (Cleaved-Glu959) (ABIN7212524)

抗原

See all ITGA7 抗体
ITGA7 (Integrin, alpha 7 (ITGA7))

适用

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人, 猴

宿主

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兔

克隆类型

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多克隆

标记

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This ITGA7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 910-990, Cleaved-Glu959

    原理

    Rabbit Anti-Cleaved-Integrin α7 LC (E959) Polyclonal Antibody

    特异性

    Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the C-terminal region of human Integrin alpha7 LC at AA range: 910-990

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ITGA7 (Integrin, alpha 7 (ITGA7))

    别名

    Integrin alpha7 LC

    背景

    ITGA7, Integrin alpha-7The protein encoded by ITGA7 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.Integrin subunit alpha 7 functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in ITGA7 are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for ITGA7.

    分子量

    25kD

    基因ID

    3679

    UniProt

    Q13683

    途径

    Integrin Complex
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