Integrin Alpha6 LC (AA 900-980), (Cleaved-Glu942) 抗体
This 兔 多克隆 antibody specifically detects Integrin Alpha6 LC in ELISA 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN7212522
发货至:
中国
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Quick Overview for Integrin Alpha6 LC (AA 900-980), (Cleaved-Glu942) 抗体 (ABIN7212522)
抗原
Integrin Alpha6 LC
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 900-980, Cleaved-Glu942
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原理
- Cleaved-Integrin α6 LC (E942) Polyclonal Antibody
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特异性
- Cleaved-Integrin α6 LC (E942) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α6 LC protein resulting from cleavage adjacent to E942.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Integrin alpha6 LC at AA range: 900-980
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亚型
- IgG
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anti-Integrin Alpha6 LC (cleaved), (Glu942) antibody
适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Integrin Alpha6 LC
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背景
- Rabbit Anti-Cleaved-Integrin α6 LC (E942) Polyclonal Antibody,ITGA6, Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD antigen CD49f,ITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.,Integrin alpha-6
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分子量
- observerd band 28kDa
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基因ID
- 3655
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UniProt
- P23229
抗原
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