ITFG2 抗体 (AA 40-120)
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Quick Overview for ITFG2 抗体 (AA 40-120) (ABIN7229200)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- ITFG2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ITFG2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human ITFG2 protein at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))
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别名
- ITFG2
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背景
- Rabbit Anti-ITFG2 Polyclonal Antibody,KICSTOR complex protein ITFG2, Integrin-alpha FG-GAP repeat-containing protein 2,ITFG2 (Integrin Alpha FG-GAP Repeat Containing 2) is a Protein Coding gene. Diseases associated with ITFG2 include Distal Arthrogryposis. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.,ITFG2
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分子量
- observerd band 49kDa
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基因ID
- 55846
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UniProt
- Q969R8
抗原
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