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ITFG2 抗体 (AA 40-120)

This anti-ITFG2 antibody is a 兔 多克隆 antibody detecting ITFG2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7229200
发货至: 中国
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Quick Overview for ITFG2 抗体 (AA 40-120) (ABIN7229200)

抗原

ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

适用

  • 18
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 11
  • 7

克隆类型

  • 9
  • 9
多克隆

标记

  • 18
This ITFG2 antibody is un-conjugated

应用范围

  • 17
  • 8
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-120

    原理

    ITFG2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of ITFG2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human ITFG2 protein at AA range: 40-120

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

    别名

    ITFG2

    背景

    Rabbit Anti-ITFG2 Polyclonal Antibody,KICSTOR complex protein ITFG2, Integrin-alpha FG-GAP repeat-containing protein 2,ITFG2 (Integrin Alpha FG-GAP Repeat Containing 2) is a Protein Coding gene. Diseases associated with ITFG2 include Distal Arthrogryposis. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.,ITFG2

    分子量

    observerd band 49kDa

    基因ID

    55846

    UniProt

    Q969R8
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