ITGA4 抗体 (pSer1027)
Quick Overview for ITGA4 抗体 (pSer1027) (ABIN7221880)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer1027
-
原理
- Integrin α4 (phospho Ser1027) Polyclonal Antibody
-
特异性
- Phospho-Integrin α4 (S1027) Polyclonal Antibody detects endogenous levels of Integrin α4 protein only when phosphorylated at S1027.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human Integrin alpha4 Phospho-Ser1027
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- ITGA4 (Integrin alpha 4 (ITGA4))
-
别名
- Integrin alpha4
-
背景
- Rabbit Anti-Integrin α4 (phospho Ser1027) Polyclonal Antibody,ITGA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, CD antigen CD49d,ITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.,Integrin alpha-4
-
基因ID
- 3676
-
UniProt
- P13612
-
途径
- Integrin Complex
抗原
-