Integrin alpha 1 抗体 (AA 920-980)
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Quick Overview for Integrin alpha 1 抗体 (AA 920-980) (ABIN7229164)
抗原
See all Integrin alpha 1 (ITGA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 920-980
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原理
- Rabbit Anti-Integrin α1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of Integrin α1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human Integrin alpha1 protein at AA range: 920-980
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Integrin alpha 1 (ITGA1)
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别名
- Integrin alpha1
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背景
- Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD antigen CD49aIntegrin α1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
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基因ID
- 3672
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UniProt
- P56199
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途径
- EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
抗原
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