INSIG2 抗体 (AA 40-120)
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Quick Overview for INSIG2 抗体 (AA 40-120) (ABIN7229148)
抗原
See all INSIG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- Rabbit Anti-INSI2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of INSI2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human INSI2 protein at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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别名
- INSI2
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背景
- Insulin-induced gene 2 protein, INSIG-2INSIG2 (Insulin Induced Gene 2) is a Protein Coding gene. Among its related pathways are Metabolism and Sterol Regulatory Element-Binding Proteins (SREBP) signalling. The protein encoded by INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
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分子量
- 24kD
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基因ID
- 51141
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UniProt
- Q9Y5U4
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途径
- ER-Nucleus Signaling
抗原
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