INPPL1 抗体 (Internal Region)
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Quick Overview for INPPL1 抗体 (Internal Region) (ABIN7217988)
抗原
See all INPPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- SHIP-2 Polyclonal Antibody
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特异性
- SHIP-2 Polyclonal Antibody detects endogenous levels of SHIP-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human SHIP-2
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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别名
- SHIP-2
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背景
- Rabbit Anti-SHIP-2 Polyclonal Antibody,INPPL1, SHIP2, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5'-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2,Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 encoded by INPPL1 is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.,Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
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分子量
- observerd band 130kDa
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基因ID
- 3636
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UniProt
- O15357
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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