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ING3 抗体

This 兔 多克隆 anti-ING3 antibody specifically detects ING3 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7229142
发货至: 中国
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Quick Overview for ING3 抗体 (ABIN7229142)

抗原

See all ING3 抗体
ING3 (Inhibitor of Growth Family, Member 3 (ING3))

适用

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人, 小鼠, 大鼠

宿主

  • 30
  • 4
  • 2

克隆类型

  • 33
  • 3
多克隆

标记

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This ING3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    ING3 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of ING3 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human ING3 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ING3 (Inhibitor of Growth Family, Member 3 (ING3))

    别名

    ING3

    背景

    Rabbit Anti-ING3 Polyclonal Antibody,Inhibitor of growth protein 3, p47ING3,Inhibitor Of Growth Family Member 3 encoded by ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.,ING3

    分子量

    observerd band 45kDa

    基因ID

    54556

    UniProt

    Q9NXR8
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