Importin 5 抗体
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北京 101111
Quick Overview for Importin 5 抗体 (ABIN7229178)
抗原
See all Importin 5 (IPO5) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IPO5 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of IPO5 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human IPO5 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Importin 5 (IPO5)
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别名
- IPO5
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背景
- Rabbit Anti-IPO5 Polyclonal Antibody,Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5,IPO5 (Importin 5) is a Protein Coding gene. Diseases associated with IPO5 include Hiv-1. Among its related pathways are Development_TGF-beta receptor signaling and HIV Life Cycle. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.,IPO5
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分子量
- observerd band 120kDa
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基因ID
- 3843
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UniProt
- O00410
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途径
- Protein targeting to Nucleus
抗原
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