IDUA 抗体
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北京 101111
Quick Overview for IDUA 抗体 (ABIN7229020)
抗原
See all IDUA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-IDUA Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of IDUA protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human IDUA protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- IDUA (Iduronidase, alpha-L- (IDUA))
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别名
- IDUA
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背景
- Alpha-L-iduronidaseIDUA encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
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分子量
- 71kD
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基因ID
- 3425
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UniProt
- P35475
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途径
- Glycosaminoglycan Metabolic Process
抗原
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