HCN4 抗体 (AA 600-680)
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北京 101111
Quick Overview for HCN4 抗体 (AA 600-680) (ABIN7228872)
抗原
See all HCN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-680
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原理
- Rabbit Anti-HCN4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of HCN4 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human HCN4 protein at AA range: 600-680
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))
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别名
- HCN4
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背景
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in HCN4 have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
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分子量
- 132kD
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基因ID
- 10021
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UniProt
- Q9Y3Q4
抗原
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