Homeobox Protein 5 (LOC101458951) 抗体
This 兔 多克隆 antibody specifically detects Homeobox Protein 5 in ELISA 和 WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7231354
发货至:
中国
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Quick Overview for Homeobox Protein 5 (LOC101458951) 抗体 (ABIN7231354)
抗原
Homeobox Protein 5 (LOC101458951)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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原理
- SHAN3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SHAN3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SHAN3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Homeobox Protein 5 (LOC101458951)
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别名
- SHAN3
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背景
- Rabbit Anti-SHAN3 Polyclonal Antibody,SH3 and multiple ankyrin repeat domains protein 3, Shank3, Proline-rich synapse-associated protein 2, ProSAP2,SHANK3 is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in SHANK3 are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in SHANK3 also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for SHANK3 but they have not yet been experimentally verified.,SHAN3
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分子量
- observerd band 191kDa
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基因ID
- 85358
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UniProt
- Q9BYB0
抗原
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